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Sunday brings the inaugural Wear-Tyne derby since 2024, but which side will celebrate – Sunderland or the Magpies?
"Throughout the majority of last season, no one would have predicted Sunderland getting promoted and challenging with Eddie Howe's Newcastle, let alone being above them in the table," remarked analyst Chris Sutton.
"It is very different now, and the way Sunderland play leads me to believe they've got a genuine opportunity."
Sutton is making predictions for all 380 Premier League games this season, against AI, fans and a variety of guests.
For week 16, he is challenged by England Gaming star Daniel 'Stingray' Ray.
Ray is competing for honours for the eLions – the Football Association's formal esports team – at the football simulation European esports championship finals tournament, which is being held at Twickenham Stadium on Saturday.
You can watch Uefa's video platform, IG Live and short-form video channels, as well as EA Sports FC Twitch and its YouTube counterpart and England's Twitch.
What are your thoughts with their predictions? Feel free to submit your own projections below.
The fan-favourite scoreline selected for each game is used in the leaderboards at the bottom of this page.
Getting the win/draw/loss right (choosing a win, draw or defeat) is worth 10 points. A perfect prediction earns forty points.
Ray, who also plays Gen City and the Premier League champions as well as England, is competing for the first time at the eEuros finals after passing the qualification rounds.
Eight players will represent their nations at the finals in a single-elimination, playing for a substantial cash prize and a prestigious spot in the world finals play-offs, with the Danish representative Anders Vejrgang looking to retain the title he won last year.
"I'm feeling really good for it," Ray said. "I've got a really good coach alongside me and practice has been going well.
"It is invariably an honour to play for your country. Of course when you are younger, you imagine doing it as an professional footballer, but when you enter this field and there is an chance to represent England, donning the national jersey is something unique.
"I overcame Vejrgang 9-4 in qualifying to get here. I've played against him recently just in practice, and in other tournaments before - but I'd not previously defeated him in a tournament before.
"For me he is the top competitor in the world so getting a win over him in a tournament like this just delivers a massive injection of confidence."
Premier League Forecasts
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The Blues were outstanding against Arsenal at the end of November, when they earned a stalemate after being reduced to 10 men, and I was thinking here we go, they could potentially be title contenders.
However, since that game, however, they were overpowered by Leeds, looked lethargic against Bournemouth and this week got defeated by Atalanta in the Champions League.
So manager Enzo Maresca desperately requires a win here to get back on track, but it is a tough ask because Everton are such a potent team.
Kiernan Dewsbury-Hall and Iliman Ndiaye are playing exceptionally and they have got a bit of form at the moment.
Current evidence suggests you would probably back Everton, while the most logical prediction would probably be a draw, but I'm going against logic.
Chelsea haven't given me any good cause to back them recently, but I just have a hunch Chelsea will emerge victorious because they are at home and they are due a win.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I'm attending this game and it will be intriguing to see what we get from the Reds.
I was delighted for Reds boss Arne Slot to get such a important victory at Inter Milan on Tuesday following all the controversy with Mohamed Salah this week.
Slot should not have to put up with that nonsense. I know Salah has been a icon for Liverpool but at its core Slot just wants to win games and there is no ulterior motive in his team selection.
Liverpool changed their tactical setup against Inter and went with a midfield diamond formation and two up top.
The media is going to be talking about whether Salah is included for this game, but the only way he is going to be brought back into the fold is if he makes amends.
Slot's attention will be on winning this game, but it is a difficult fixture.
It's fair to say it is the same for most teams but I find Brighton so hard to predict. I always feel they have got a goal in them, but they are defensively susceptible too.
Liverpool need to get back to stringing wins together, but I am not sure how much their energy spent at the San Siro will have taken out of them.
I've selected a couple of Brighton players in my Fantasy Premier League side, so they will probably lose now - but I do fancy them to get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Black Cats have had the benefit of a free week while Newcastle had to work so hard against Bayer Leverkusen on Wednesday, only to be pegged back late on.
With the exception of their excellent performance against Everton a couple of weeks ago, Newcastle's away form hasn't been great, especially straight after they've played in the Champions League.
The pattern suggests that trend to continue on Sunday, and their tiredness is likely to be a key element in how this game goes because of their rivals' high press.
We saw how relentless Regis le Bris's side are. They dominated the Gunners, and it was a joy to watch.
Commentators talks about how Granit Xhaka has been brilliant for the Black Cats, and he has been superb, but Noah Sadiki, who plays next to him, has also been one of the signings of the season and warrants praise too.
All signs point to this being the best game|most exciting fixture